Dosage: | 40mg, 20mg, 10mg, 5mg. |
---|---|
Form of release: | Tablets (30 pcs. in package). |
Indications: | Asthma, arthritis, allergies, inflammation. |
Manufacturer: | PharmaHealth Inc. |
Description: | Prednisone 40 mg is a powerful anti-inflammatory used for a variety of autoimmune and allergic conditions. Quickly relieves symptoms and helps restore quality of life. It is recommended under the supervision of a physician. |
Prednisone is available through licensed online pharmacies, but in most countries (including the US, EU, and UK) it is strictly prescription-only. Always use pharmacies that verify prescriptions and provide certified pharmacists. According to Drugs.com, purchasing Prednisone without a valid prescription contradicts medical guidelines.
Prednisone is a synthetic glucocorticoid corticosteroid with anti-inflammatory and immunosuppressive properties. It is a prodrug—converted by the liver into its active form prednisolone (Wikipedia).
Prednisone enters cells and binds to intracellular glucocorticoid receptors. This complex translocates to the nucleus and modulates gene expression, upregulating anti-inflammatory proteins and downregulating pro-inflammatory cytokines such as IL-1 and TNF-α (MedlinePlus).
This video provides a visual explanation of Prednisone’s pharmacological effects and usage.
Condition | Examples |
---|---|
Autoimmune disorders | Rheumatoid arthritis, lupus |
Allergic conditions | Severe asthma, angioedema |
Oncology | Leukemia, lymphoma |
Hematologic | Immune thrombocytopenia |
Transplantation | Organ rejection prevention |
Endocrine | Addison’s disease |
Prednisone is usually taken orally in tablet form (1–20 mg). It is also available as a liquid or via IV (as prednisolone) for hospital use (Drugs.com).
Indication | Initial Dose | Maintenance |
---|---|---|
Asthma | 20–40 mg/day | 5–10 mg/day |
Lupus | 30–60 mg/day | 10–20 mg/day |
Allergy | 30–50 mg/day | Short-term |
Addison’s | 5–7.5 mg/day | Replacement |
Long-term use increases the risk of adrenal suppression, osteoporosis, diabetes, and cataracts. Physicians aim to use the lowest effective dose (Wikipedia).
Sudden withdrawal after prolonged use can lead to adrenal insufficiency. Always taper gradually under physician guidance.
Drug | Potency | Duration |
---|---|---|
Prednisone | 4 | 18–36 hrs |
Prednisolone | 4 | 18–36 hrs |
Dexamethasone | 25 | 36–54 hrs |
* The information provided here is intended to be a brief summary. Please contact Star H Equine Insurance and/or review your policy for more detailed information.
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